Yes. Thyroid disease can affect kidney function. The thyroid hormone has various effects on the body. It impacts the kidney, heart, and vascular systems. Thyroid dysfunction can cause significant changes in renal and cardiovascular functions. With respect to kidney function, researchers associate hypothyroidism with reduced renal plasma flow (RPF) and low glomerular filtration rate (GFR). (GFR refers to Glomerular Filteration Rate. It is the volume of plasma that is filtered by the glomeruli of the kidney per unit of time. It determines how well the kidneys work.)
According to the Indian Journal of Endocrinology and Metabolism, impairment in kidney and thyroid functions affect each other. When there is an impairment in the kidney or thyroid function, various interactions take place in each other organ disease states. The thyroid hormones affect renal development and physiology. There are certain pre-renal and intrinsic renal effects of thyroid hormones which increases the renal blood flow and the glomerular filtration rate (GFR).
Researchers associate hyperthyroidism with an increased GFR and increased renin-angiotensin-aldosterone activation. Patients who suffer from chronic kidney disease (CKD) generally have a low T3 syndrome. This is at present considered a part of an atypical nonthyroidal illness. The incidence of primary hypothyroidism and subclinical hypothyroidism also increases in CKD patients.
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