Last Updated on April 27, 2022 by Shabnam Sengupta
Maybe. Research states that about 67% to 85% of women with PCOS (Polycystic Ovary Syndrome) are vitamin D deficient, which means they don’t have the recommended amount of vitamin D in their bodies. These low levels of vitamin D seem to aggravate PCOS symptoms.
Research indicates that high prevalence of vitamin D deficiency has been related with metabolic syndrome. Low 25(OH)D* levels may lead to worsen symptoms of PCOS like insulin resistance, ovulatory, menstrual irregularities, infertility, hyperandrogenism, obesity and elevate the risk of cardiovascular diseases. A significant correlation is found between Low 25(OH)D levels and insulin resistance in women with PCOS. Thus, the genes involved in vitamin D metabolism may cause PCOS.
Many observational studies suggest a possible role of vitamin D in an inverse association between vitamin D status and metabolic disturbances in PCOS. However, it is still hard to draw a definite conclusion in the causal relationship due to inconsistent findings from the studies.
Due to the wide heterogeneity of symptoms and signs of PCOS (Polycystic Ovary Syndrome) predisposed by different genetic and environmental factors, it may not be easy to determine functional correlations between Vitamin D and PCOS. In addition, there are many interlinking factors which may affect the individual phenotypic expression of women with PCOS.
*25(OH)D is a stable vitamin D metabolite that is used for the assessment of vitamin D status.
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