It seems so that the type 1 diabetes is genetic. Type 1 diabetes and type 2 diabetes are different. The tendency to develop type 1 diabetes is passed through generations but the exact pattern of inheritance is still not clear. In the majority of cases, the type 1 diabetes can pass through genes from mother or father. However, the condition can also occur due to environmental factors such as viruses triggering the condition. These factors induce autoimmune destruction of pancreatic beta (β) cells which attack and destroy cells that make insulin. Lifestyle doesn’t have a major role in inducing type 1 diabetes.
Is there a specific gene for type 1 diabetes?
It seems so. As type 1 diabetes may pass through genes, researchers have tried to find specific genes for type 1 diabetes that put people at a higher risk. The available evidence only speculates that certain genetic structures put humans at a greater risk of type 1 diabetes. Certain genes such as HLA-DQA1, HLA-DQB1, and HLA-DRB1 can increase the chance of type 1 diabetes. These genes guide proteins that instruct the immune system to behave in a certain way. Any change in the normal course of instructions induces an abnormal chain of events that causes type 1 diabetes.
Is genetic testing for type 1 diabetes possible?
Yes. Genetic testing for type 1 diabetes is possible. An antibodies test helps determine the presence of type 1 diabetes even before symptoms appear. This test measures antibodies to insulin, to islet cells in the pancreas and to the glutamic acid decarboxylase enzyme. Abnormal levels determine the risk of developing symptomatic type 1 diabetes in the near future.
Studying the genes of a person helps determine the risk of type 1 diabetes. This study can help to prepare a treatment plan way before the disease even affects the body. This can help the community at a larger level by reducing the risk of type 1 diabetes in people who are at a higher risk.
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