Maybe. Smoking can be an important modifiable risk factor for PCOS (Polycystic Ovary Syndrome). It can play a role in various reproductive disorders. The chemical constituents found in cigarette smoke can impact the ovary, uterus, etc. According to a study, smoking may devastatingly affect women suffering from PCOS in their reproductive age. It does not only increase cardiovascular risk, it can also adversely affect the cholesterol levels and reproductive hormones.
Higher levels of serum cholesterol, triglycerides, very low density lipoproteins (VLDL) and low density lipoproteins (LDL) and lower levels of high density lipoproteins (HDL) are found in the smokers than the non-smokers. The study suggests that nicotine and smoking can decrease estrogen levels by inhibiting aromatase activity. Smoking can increase both metabolic syndrome and hyperandrogenism in women with PCOS.
Another study also suggests that smoking may worsen the already high risk for metabolic syndrome in women with PCOS. Smoking can also influence insulin in the body. According to the study, increased free testosterone and risk of insulin resistance were seen among the women suffering from PCOS who were smoking. Although these biologically theoretical explanations are plausible, further studies are warranted to understand the underlying mechanisms of smoking in the development of PCOS.
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