Last Updated on April 26, 2022 by Shabnam Sengupta
Yes. Fluorine may intensify the mechanisms of PCOS (Polycystic Ovary Syndrome) development via increased insulin resistance and disturbed thyroid-stimulating hormone (TSH) synthesis even at reference levels.
A research conducted in 2019 concluded that Fluorine, even in concentrations regarded as proper, takes part in the development of PCOS. It increases the synthesis of TSH and increases insulin resistance. Higher insulin resistance leads to the reduced synthesis of SHBG transport protein. The key factor in the development of PCOS is testosterone, and fluorine facilitates disruptions in carbohydrates and lipids metabolism leading to increased levels of androgens in blood. Since high androgen levels (male hormones) prevent the ovaries from releasing eggs (ovulation) that causes irregular menstrual cycles, it worsens PCOS.
Similarly, fluorine can also cause insulin resistance. Increased insulin levels cause the ovaries to produce and release androgens. Increased male hormones, in turn, suppress ovulation and contribute to other symptoms of PCOS (Polycystic Ovary Syndrome).
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