Deadly mpox virus identified in people with advanced HIV: Lancet

Just In

Last Updated on February 23, 2023 by Anshima Gupta

London, Feb 22 (IANS) An international team of clinicians has identified a severe form of mpox — formerly known as monkeypox — with high mortality in people with advanced HIV who have weaker immune systems.

The majority of mpox infections in the multi-country outbreak, which began in 2022, occurred in sexual networks of gay, bisexual and other men who have sex with men. About 38-50 per cent of people diagnosed with mpox in 2022 also live with HIV, the vast majority of whom are on HIV treatment and living healthy lives.

The team led by Queen Mary University of London and the Fight Infections Foundation/Hospital Germans Trias of Barcelona looked at 382 people with advanced HIV disease and mpox, including 27 of the 60 people (at the time of writing) reported to have died of mpox during the multi-country outbreak.

In the paper published in the journal The Lancet, they described a very severe form of mpox characterised by widespread, large, necrotising skin lesions; high rates of severe infections; and, in some cases, unusual lung lesions.

This form of the disease carries a 15 per cent mortality in people with advanced HIV disease and immunosuppression. All 27 deaths occurred within this group.

The study provides evidence that the disease is behaving differently and very concerningly in people with advanced HIV disease and immunosuppression.

“We describe a severe form of mpox affecting mostly young men who have sex with men and which results in death in 15 per cent of people with advanced HIV. When clinicians recognise necrotising skin lesions and/or lung involvement, they should use a differentiated clinical pathway and an intensified approach,” said Oriol Mitja, Associate Professor of Infectious Disease and Global Health, Fight Infectious Diseases Foundation, University Hospital Germans Trias i Pujol.

Mitja also called on health authorities to “prioritise the vaccination of people living with HIV, particularly in countries with low levels of diagnosis or without universal free access to antiretroviral treatment.”

Most mpox deaths have occurred in countries where there are low levels of HIV diagnosis and/or without universal access to antivirals for mpox and/or HIV and without access to intensive care units. A concerted global effort is needed to ensure equitable access to antivirals and vaccines in countries where the interaction of uncontrolled HIV infection and mpox is more prevalent.

The researchers have also called for the new form of mpox to be added to the World Health Organization and Center for Disease Control list of severe infections that are considered particularly dangerous to people with advanced HIV disease. They also recommend that all people with mpox be tested for HIV.

Disclaimer: Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can futher read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

History
First published on:

Disclaimer
Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can further read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

More in

Questions
Fact Check
Interviews
Stories
Videos

Last Updated on February 23, 2023 by Anshima Gupta

Disclaimer: Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can futher read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

Last Updated on February 23, 2023 by Anshima Gupta

Disclaimer: Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can futher read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

Last Updated on February 23, 2023 by Anshima Gupta

Disclaimer: Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can futher read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

Last Updated on February 23, 2023 by Anshima Gupta

Disclaimer: Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can futher read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

Last Updated on February 23, 2023 by Anshima Gupta

Disclaimer: Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can futher read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

More in

Questions
Fact Check
Interviews
Stories
Videos

Last Updated on February 23, 2023 by Anshima Gupta

Disclaimer: Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can futher read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

Last Updated on February 23, 2023 by Anshima Gupta

Disclaimer: Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can futher read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

Last Updated on February 23, 2023 by Anshima Gupta

Disclaimer: Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can futher read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

Last Updated on February 23, 2023 by Anshima Gupta

Disclaimer: Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can futher read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

Last Updated on February 23, 2023 by Anshima Gupta

Disclaimer: Medical Science is an ever evolving field. We strive to keep this page updated. In case you notice any discrepancy in the content, please inform us at [email protected]. You can futher read our Correction Policy here. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website or it's social media channels. Read our Full Disclaimer Here for further information.

- Advertisement -spot_img
Read More